Methanol → HCID 19592776, compound

Participants

Reaction Steps

A suspension of 3-chloromethyl-1,4-dihydro-8-nitro-4-oxoquinoline (2 g) in dichloromethane (70 ml) and methanol (30 ml) was refluxed for 15 minutes and concentrated in vacuo. The crystalline residue was suspended in hot methanol (30 ml), and the mixture was allowed to stand to ambient temperature. The resulting precipitates were collected by filtration to give 1,4-dihydro-3-methoxymethyl-8-nitro-4-oxoquinoline (1.5 g).

Provenance & Evidence