HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 178521896, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 19592577 | HCID 19592577 | — |
| Solvent | 1,3-Dimethyl-2-imidazolidinone | HCID 6661 | — |
| Product | HCID 178521896 | HCID 178521896 | 87.3% |
Reaction Steps
A mixture of 8-(2,6-dichlorobenzoylamino)-4-(2,6-dichlorobenzoyloxy)quinazoline (40 mg) and imidazole (53.7 mg) in 1,3-dimethyl-2-imidazolidinone (0.6 ml) was stirred for 1 hour at ambient temperature. Cold water was added to the mixture, and the resulting precipitates were collected by filtration to give 8-(2,6-dichlorobenzoylamino)-1,4-dihydro-4-oxoquinazoline (23 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06008230 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-cda07352503b4f91a6a265b693a97eae |
| Source note | uspto-grants-1999_12 |