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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 613544Generated: October 31, 2026

Imidazole → HCID 178521896, compound

https://huagongshe.com/reaction/613544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantWaterHCID 962—
ReactantHCID 19592577HCID 19592577—
Solvent1,3-Dimethyl-2-imidazolidinoneHCID 6661—
ProductHCID 178521896HCID 17852189687.3%

Reaction Steps

A mixture of 8-(2,6-dichlorobenzoylamino)-4-(2,6-dichlorobenzoyloxy)quinazoline (40 mg) and imidazole (53.7 mg) in 1,3-dimethyl-2-imidazolidinone (0.6 ml) was stirred for 1 hour at ambient temperature. Cold water was added to the mixture, and the resulting precipitates were collected by filtration to give 8-(2,6-dichlorobenzoylamino)-1,4-dihydro-4-oxoquinazoline (23 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06008230
Source datasetuspto-grants-1999_12
ORD IDord-cda07352503b4f91a6a265b693a97eae
Source noteuspto-grants-1999_12