Phenylboronic Acid → 4-Phenyl-1,3-Dihydroxybenzene

HRID 613780Notes

Reaction equation

HRID 613780 reaction equation
[C:1]1(B(O)O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C[O:11][C:12]1[CH:17]=[CH:16][C:15](Br)=[C:14]([O:19]C)[CH:13]=1>>[C:1]1([C:15]2[CH:16]=[CH:17][C:12]([OH:11])=[CH:13][C:14]=2[OH:19])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 872661-Bromo-2,4-dimethoxybenzene

Product 1

HCID 110195784-Phenyl-1,3-Dihydroxybenzene

Procedure

This compound was prepared using essentially the same procedure as that used in Example 3 with the difference that phenylboronic acid 17 (Aldrich Chemical) was used in place of 2-napthylboronic acid 13, and 1,3-dimethoxy-4-bromobenzene 15 was used in place of 1,3-dimethoxy-4-bromo-2-fluorobenzene 12.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-deb229f505cb418ca29ddeb710cde3bc
Source dataset
uspto-grants-1999_12
Patent number
US06008379

Reaction notes

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