Sodium Hydroxide → HCID 86736375, compound

Participants

Reaction Conditions

Reaction Steps

A stirred solution of 4.2 g. of ethyl 2-(1-cyclohexyl-3-pyrrolidinylaminocarbonyl)oxanilate hydrochloride in 20 ml. of 50% aqueous ethanol was treated dropwise with 19.5 ml. of 1.03 N sodium hydroxide. After thirty minutes the solution was heated to 50° C. and poured into 130 ml. of boiling ethanol. After the mixture cooled to room temperature it was kept at 4° C. for two days and the amorphous sodium salt was collected by filtration.

Provenance & Evidence