Sodium ethoxide → HCID 86736386, compound

HRID 614224Notes

Reaction equation

HRID 614224 reaction equation
[CH2:1]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH:9]([P:22](=[O:25])([O-:24])[O-:23])[NH:10][CH:11]1[CH2:16][C:15]([CH3:18])([CH3:17])[N:14]([CH3:19])[C:13]([CH3:21])([CH3:20])[CH2:12]1)[CH3:2].CC[O-].[Na+].O.O.[Ni:32](Cl)Cl>C(O)C>[Ni:32].[OH2:23].[CH2:1]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH:9]([P:22](=[O:23])([OH:24])[OH:25])[NH:10][CH:11]1[CH2:12][C:13]([CH3:20])([CH3:21])[N:14]([CH3:19])[C:15]([CH3:18])([CH3:17])[CH2:16]1)[CH3:2].[CH2:1]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH:9]([P:22](=[O:23])([OH:24])[OH:25])[NH:10][CH:11]1[CH2:12][C:13]([CH3:20])([CH3:21])[N:14]([CH3:19])[C:15]([CH3:18])([CH3:17])[CH2:16]1)[CH3:2]

Participants

5

Reactant 3

HCID 2723922Sodium ethoxideHCID 10942802Nickel chloride dihydrateHCID 86736387HCID 86736387, compound

Product 1

HCID 86736386HCID 86736386, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

18.8 g (0.05 mol) of the ethyl-1-[(1,2,2,6,6-pentamethyl-4-piperidyl)-amino]-n-heptyl-phosphonate from Example 2 are dissolved in 400 ml of ethanol with the addition of 3.40 g (0.05 mol) of sodium ethylate. A solution of 4.14 g (0.025 mol) of nickel chloride dihydrate in 100 ml of ethanol is added dropwise to this solution at 25° and the mixture is stirred at 25° for 3 hours. The sodium chloride which has precipitated out is now filtered off, the solvent is evaporated off and the residue is extracted with ether. After volatilising the solvent, the extract is dried for 10 hours at a temperature of 60° and under a pressure of 11 mm Hg. Ni-di-{ethyl-1-[(1,2,2,6,6-pentamethyl-4-piperidyl)-amino]-n-heptyl-phosphonate}-monohydrate is obtained as a green-yellow solid product. It is soluble in hexane at room temperature.

Workup

  1. customThe sodium chloride which has precipitated out
  2. filtrationis now filtered off
  3. customthe solvent is evaporated off
  4. extractionthe residue is extracted with ether
  5. customthe extract is dried for 10 hours at a temperature of 60° and under a pressure of 11 mm Hg

Sources & evidence

ORD record
ord-240875c488024ed8b68d9f3ea8032487
Source dataset
uspto-grants-1979_03
Patent number
US04144224

Reaction notes

Loading…