HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl chloroformate → phenyl N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyrimidinyl)carbamate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 2-(2-Diisopropylaminoethylamino)-4,6-dimethylpyrimidine | HCID 23349900 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | phenyl N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyrimidinyl)carbamate hydrochloride | HCID 21329151 | — |
Reaction Steps
A solution of 2-(2-diisopropylaminoethylamino)-4,6-dimethylpyrimidine (12.5 g., 0.05 mole) in 50 ml of benzene is added to a solution of phenyl chloroformate in 50 ml of benzene. After 72 hours, the solid product is collected and recrystallized from acetone to give phenyl N-(2-diisopropylaminoethyl)-N-(4,6-dimethyl-2-pyrimidinyl)carbamate hydrochloride melting at 190°-202° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04144338 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-161798b1ca10448ca0d4f240f911854d |
| Source note | uspto-grants-1979_03 |