Benzyl Chloride → HCID 20264049, compound

HRID 614426Notes

Reaction equation

HRID 614426 reaction equation
[OH:1][C:2]1[C:3]([CH3:12])=[N:4][CH:5]=[C:6]([CH:10]=[CH2:11])[C:7]=1[CH2:8][OH:9].C(=O)([O-])[O-].[K+].[K+].[CH2:19](Cl)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>CC(C)=O>[CH3:12][C:3]1[C:2]([O:1][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:7]([CH2:8][OH:9])[C:6]([CH:10]=[CH2:11])=[CH:5][N:4]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 13066945HCID 13066945, compound

Product 1

HCID 20264049HCID 20264049, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a mixture of 0.1 mole 3-hydroxy-4-hydroxymethyl-2-methyl-5-vinylpyridine in 500 ml. of acetone and 25 gm. potassium carbonate is added 0.11 mole of benzyl chloride. The reaction mixture is stirred overnight, filtered, and the acetone removed in vacuo to yield 2-methyl-3-benzyloxy-4-hydroxymethyl-5-vinylpyridine.

Workup

  1. filtrationfiltered
  2. customthe acetone removed in vacuo

Sources & evidence

ORD record
ord-5298e9c0e56640caae8ab71401dd074a
Source dataset
uspto-grants-1979_03
Patent number
US04144342

Reaction notes

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