HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Ethanediamine, N1,N1-bis(1-methylethyl)- → Pramiracetam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Ethanediamine, N1,N1-bis(1-methylethyl)- | HCID 8459 | — |
| Reactant | Ethyl 2-oxopyrrolidine-1-acetate | HCID 109094 | — |
| Product | Pramiracetam | HCID 51712 | — |
Reaction Steps
From 17.1 g. of ethyl 2-oxo-1-pyrrolidineacetate and 21 g. of 2-(diisopropylamino)ethylamine [J.A.C.S. 78, 486 (1956)], following the procedure of Example 1, there is obtained N-[2-[bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide; b.p. 164° C./0.15 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-6e8481b23a054f1b87540270340adc82 |
| Source note | uspto-grants-1979_03 |