HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-3-[2,6-Dimethylpiperidinyl]propylamine → cis-(+/-)-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-alpha-methyl-2-oxo-1-pyrrolidineacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-3-[2,6-Dimethylpiperidinyl]propylamine | HCID 7176132 | — |
| Reactant | Ethyl alpha-methyl-2-oxo-1-pyrrolidineacetate | HCID 15044021 | — |
| Product | cis-(+/-)-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-alpha-methyl-2-oxo-1-pyrrolidineacetamide | HCID 22807215 | — |
Reaction Steps
From 9.25 g. of ethyl α-methyl-2-oxo-1-pyrrolidineacetate and 10.5 g. of cis-3-(2,6-dimethyl-1-piperidinyl)propylamine, following the procedure of Example 21, there is obtained cis-(±)-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-methyl-2-oxo-1-pyrrolidineacetamide; b.p. 165°-170° C./0.1 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-80f1fc880dbf4760a606967af394d539 |
| Source note | uspto-grants-1979_03 |