Ethoxalyl chloride → HCID 12909301, compound

HRID 614530Notes

Reaction equation

HRID 614530 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][C:8]3=[N:11][C:12]([C:14]([O:16][CH3:17])=[O:15])=[CH:13][N:7]3[C:6]=2[CH:18]=1.[C:19](Cl)(=[O:25])[C:20]([O:22][CH2:23][CH3:24])=[O:21]>CN(C)C=O>[C:19]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][C:8]3=[N:11][C:12]([C:14]([O:16][CH3:17])=[O:15])=[CH:13][N:7]3[C:6]=2[CH:18]=1)([C:20]([O:22][CH2:23][CH3:24])=[O:21])=[O:25]

Participants

4

Reactant 2

HCID 20884Ethoxalyl chlorideHCID 12909299HCID 12909299, compound

Product 1

HCID 12909301HCID 12909301, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

By the procedure of Step C in Example 1, methyl 8-amino-4H-imidazo-[2,1-c][1,4]-benzoxazine-2-carboxylate and ethyl chlorooxalate were reacted in dimethylformamide as solvent to obtain a 65% yield of methyl 8-(ethoxalylamino)-4H-imidazo-[2,1-c][1,4]-benzoxazine-2-carboxylate with a melting point of 186°-8° C.

Sources & evidence

ORD record
ord-0a2a16f80026419ab071050a51ca05ce
Source dataset
uspto-grants-1979_03
Patent number
US04145419

Reaction notes

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