HCID 70572688, compound → HCID 21315520, compound

HRID 614575Notes

Reaction equation

HRID 614575 reaction equation
[C:1](O)(=O)/[CH:2]=[CH:3]\[C:4](O)=O.CN1C[C@@H:13]2[C:15]3[CH:27]=[CH:26][CH:25]=[CH:24][C:16]=3O[C:18]3[CH:23]=[CH:22]C=C[C:19]=3[C@@H:12]2C1.[CH3:28][N:29]1C[C@@H]2C3C=C(C)C=CC=3OC3C=CC=CC=3[C@@H]2[CH2:30]1.C(O)(=O)/C=C\C(O)=O.CN1C[C@@H]2C3C=C(Cl)C=CC=3OC3C=CC=CC=3[C@@H]2C1.C(O)(=O)/C=C\C(O)=O.CN1CC[C@@H]2C3C=CC=CC=3OC3C=CC=CC=3[C@@H]2C1.C(O)(=O)/C=C\C(O)=O.CN1CC[C@@H]2C3C=CC=CC=3CC3C=CC=CC=3[C@@H]2C1>>[CH3:28][N:29]1[CH2:30][CH:3]2[C:4]3[CH:22]=[CH:23][CH:18]=[CH:19][C:12]=3[CH2:13][C:15]3[CH:27]=[CH:26][CH:25]=[CH:24][C:16]=3[CH:2]2[CH2:1]1

Participants

6

Reactant 5

HCID 70572688HCID 70572688, compoundHCID 86736414HCID 86736414, compoundHCID 867364151H-Dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 5-chloro-2,3,3a,12b-tetrahydro-2-methyl-, (3aR,12bS)-rel-, (2Z)-2-butenedioate (1:1)HCID 86736416HCID 86736416, compoundHCID 86736418HCID 86736418, compound

Product 1

HCID 21315520HCID 21315520, compound

Procedure

cis-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3;6,7] oxepino[4,5-c]pyrrole maleate, m.p. 143-144° C.; cis-2,5-dimethyl-2,3,3a,12b-tetrahydro-1H-dibenz[ 2,3;6,7]oxepino[4,5-c]pyrrole, m.p. 99-101° C.; cis-2-methyl-5-chloro-2,3,3a,12b-tetrahydro-1H-dibenz[ 2,3;6,7]oxepino[4,5-c]pyrrole maleate, m.p. 116-169° C.; cis-2-methyl-1,2,3,4,4a,13b-hexahydro-dibenz[2,3;6,7] oxepino[4,5-c]pyridine maleate, m.p. 174-1750° C.; cis-2-methyl-2,3,4,4a,9,13b-hexahydro-1H-dibenzo[1,2;5,6] cyclohepta[3,4-c]pyridine maleate, m.p. 207-209° C. and the corresponding trans isomer (maleate salt), m.p. 175-176° C.

Sources & evidence

ORD record
ord-ac7e75df02ff4a7bbf4464610f11502d
Source dataset
uspto-grants-1979_03
Patent number
US04145434

Reaction notes

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