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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 614645Generated: October 30, 2026

2-Thiopheneacetyl chloride → HCID 131711462, compound

https://huagongshe.com/reaction/614645

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneacetyl chlorideHCID 162362—
Reactant3-Carbamoyloxymethyl-7-amino-3-cephem-4-carboxylic acidHCID 12784759—
ReactantHCID 70567479HCID 70567479—
ProductHCID 131711462HCID 131711462—

Reaction Steps

A third 1 μl portion of the 7-amino-3-carbamoyloxymethyl-3-cephem-4-carboxylic acid-containing solution, prepared as reported in Example 11, was treated as described in Example 11, except that the acyl halide was 2-thiopheneacetyl chloride, and the resulting product was 7-(2-(2-thienyl)acetamido)-3-carbamoyloxymethyl-3-cephem-4-carboxylic acid. It exhibited an RCV value of 0.39.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04145538
Source datasetuspto-grants-1979_03
ORD IDord-329b4637649d4ddc903830acd528fa1e
Source noteuspto-grants-1979_03