Dimethylformamide dimethyl acetal → HCID 70603237, compound

Participants

Reaction Steps

15 g (45 mmols) of 2-amino-4-phenyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester were warmed to 100° C. together with 10 g (84 mmols) of dimethylformamide dimethyl acetal and the mixture was stirred for about 60 minutes at this temperature. The reaction mass solidified whilst cooling and was suspended in a little ether, filtered off and recrystallised from ethanol. Melting point: 131° C. Yield: 13.7 g (79%)

Provenance & Evidence