Potassium Nitrate → HCID 21327506, compound

Participants

Reaction Steps

To a solution of 3.13 g of 1-(2-pyridylmethyl)-4-phenyl-2(1H)-quinazolinone in 10 ml of concentrated sulfuric acid was added dropwise a solution of 1 g of potassium nitrate in 3 ml of concentrated sulfuric acid with cooling by an ice bath. The resulting mixture was stirred at room temperature for 3 hours and then poured onto cracked ice. The precipitate was collected by filtration, washed successively with water and ammonia water and dried to give 1-(2-pyridylmethyl)-4-phenyl-6-nitro-2(1H)-quinazolinone. Recrystallization from chloroform gave colorless fine crystals, m.p. 175°-176° C.

Provenance & Evidence