Urea → Einecs 256-823-2

HRID 614979Notes

Reaction equation

HRID 614979 reaction equation
[NH2:1][C:2]([NH2:4])=[O:3].N[C:6](N)=[O:7].C(O)(=O)C[CH2:11][CH2:12][C:13]([OH:15])=[O:14]>>[NH2:1][C:2]([NH2:4])=[O:3].[C:6]([OH:7])(=[O:3])[CH2:11][CH2:12][C:13]([OH:15])=[O:14]

Participants

3

Reactant 2

HCID 1176UreaHCID 7345679421835-54-1

Product 1

HCID 6452277Einecs 256-823-2

Procedure

35 g. of urea was further added to the mother liquor with the urea-glutaric acid adduct removed and dissolved at 50° C. The resulting solution was then cooled to and allowed to stand at 15° C. for 5 hours to crystallize a urea-succinic acid adduct out of the solution. By filtration, 47 g. of urea-succinic acid adduct (including 21 g. of succinic acid) was obtained. The obtained urea-succinic acid adduct was dissolved in 500 g. of methanol at 30° C. and the resulting solution was treated with AMBERLYST 15 as used in Example 3 to remove urea. After removal of 300 g. of methanol, the solution was cooled to and allowed to stand at 20° C. to precipitate succinic acid. By filtration, 18 g. of succinic acid having a purity of 97.9% was obtained.

Workup

  1. customremoved
  2. dissolutiondissolved at 50° C
  3. temperatureThe resulting solution was then cooled to and
  4. customto crystallize a urea-succinic acid adduct out of the solution
  5. filtrationBy filtration, 47 g

Sources & evidence

ORD record
ord-7b1202736cb24021927d9f28e196372a
Source dataset
uspto-grants-1979_03
Patent number
US04146730

Reaction notes

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