反应详情

温度

160 °C

6 grams 3,5-dimethyl-1-phenyl-pyrazol-4-acetic acid-methyl-ester and 80 milliliters ammonia solution in methanol were mixed and the mixture heated in an autoclave to 160° C. for 6 hours. The reaction mixture was evaporated to dryness. 4.6 grams 3,5-dimethyl-1-phenyl-pyrazol-4-acetamide, melting at 160°-170° C., were obtained, representing a yield of 81%.

1. customThe reaction mixture was evaporated to dryness