Sodium Hydroxide → Spiro(cyclopentane-1,2'(1'H)-(1,3,5)triazino(1,2-a)benzimidazol)-4'(3'H)-one, 3'-methyl-

HRID 615096Notes

Reaction equation

HRID 615096 reaction equation
CNC([N:5]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[N:7]2[C:14](=[O:23])[N:15]([CH3:22])[C:16]3([N:21]=[C:6]12)[CH2:20][CH2:19][CH2:18][CH2:17]3)=O.[OH-].[Na+]>C1COCC1>[CH3:22][N:15]1[C:16]2([CH2:20][CH2:19][CH2:18][CH2:17]2)[NH:21][C:6]2=[N:5][C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=3[N:7]2[C:14]1=[O:23]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 13454053HCID 13454053, compound

Product 1

HCID 159113Spiro(cyclopentane-1,2'(1'H)-(1,3,5)triazino(1,2-a)benzimidazol)-4'(3'H)-one, 3'-methyl-

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The reaction product of Example 26 was hydrolyzed by 10% aqueous sodium hydroxide and THF to give the title compound, employing the procedure of Example 1, paragraph 2. The product was recrystallized from acetone to give a solid, mp 180°-182° C. The confirmatory elemental analysis is shown in Table III.

Sources & evidence

ORD record
ord-361df454535740fdb7be749e27cfde28
Source dataset
uspto-grants-1985_02
Patent number
US04497650

Reaction notes

Loading…