4-Chlorophenol → HCID 15593675, compound

HRID 615126Notes

Reaction equation

HRID 615126 reaction equation
Cl[C:2]1[C:7](=[O:8])[C:6]([Cl:9])=[N:5][S:4][N:3]=1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1.[OH-].[Na+]>O>[Cl:9][C:6]1[C:7](=[O:8])[C:2]([O:17][C:14]2[CH:15]=[CH:16][C:11]([Cl:10])=[CH:12][CH:13]=2)=[N:3][S:4][N:5]=1

Participants

5

Reactant 3

HCID 46844-ChlorophenolHCID 14798Sodium HydroxideHCID 3540263,5-Dichloro-4H-1,2,6-thiadiazin-4-one

Product 1

HCID 15593675HCID 15593675, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A suspension of 1.83 g of 3,5-dichloro-4H-1,2,6-thiadiazin-4-one in 100 ml of water is stirred mechanically at room temperature while a solution of 1.29 g of p-chlorophenol, 20 ml of H2O and 5 ml of 2N aqueous sodium hydroxide solution is added dropwise to it. The mixture is stirred an additional 1 hour. The resulting precipitate is collected and recrystallized from alcohol. The white crystals melt at 142°-145°. The compounds described in Table II can be prepared by the same procedure as Example 2 substituting the appropriate phenol for p-chlorophenol.

Workup

  1. additionis added dropwise to it
  2. customThe resulting precipitate is collected
  3. customrecrystallized from alcohol
  4. custommelt at 142°-145°
  5. customcan be prepared by the same procedure as Example 2 substituting the appropriate phenol for p-chlorophenol

Sources & evidence

ORD record
ord-9bc7fcfdcfe24c8ca1dcb746e1947cc8
Source dataset
uspto-grants-1985_02
Patent number
US04497807

Reaction notes

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