反应详情

A solution of 3.66 g of 3,5-dichloro-4H-1,2,6-thiadiazin-4-one in 30 ml of methanol is kept at 0°-5° C. and stirred while a solution of 2.40 g of sodium methoxide in 30 ml of methanol is added dropwise to it. The reaction mixture is stirred at room temperature 2 hours longer, then mixed with 200 ml of ice water. The precipitate is collected, washed with water, dried, and recrystallized from hexane to yield pale yellow needles, mp 159°-161°.

1. customis kept at 0°-5° C.
2. additionis added dropwise to it
3. customThe precipitate is collected
4. washwashed with water
5. customdried
6. customrecrystallized from hexane
7. customto yield pale yellow needles, mp 159°-161°