m-Chloroperbenzoic acid → HCID 178504633, compound

HRID 615130Notes

Reaction equation

HRID 615130 reaction equation
[NH2:1][C:2]1[NH:3][S:4](=[O:13])(=[O:12])[N:5]=[C:6]([CH2:8][CH2:9][S:10][CH3:11])[N:7]=1.ClC1C=CC=C(C(OO)=[O:22])C=1>CO.C(Cl)(Cl)Cl>[NH2:1][C:2]1[NH:3][S:4](=[O:13])(=[O:12])[N:5]=[C:6]([CH2:8][CH2:9][S:10]([CH3:11])=[O:22])[N:7]=1

Participants

5

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 178503673HCID 178503673, compound

Product 1

HCID 178504633HCID 178504633, compoundYield 96.9%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6212ChloroformSolvent

Procedure

To a solution of 3-amino-5-[2-(methylthio)ethyl]-1,2,4,6-thiatriazine-1,1-dioxide (1.22 gm, 5.5 mmol) in warm methanol (20 ml) there was added dropwise a solution of 80% pure m-chloroperbenzoic acid (1.2 gm, 5.6 mmol) in chloroform (20 ml). The product crystallized from solution during the addition and was collected by filtration and washed with diethyl ether to give 1.27 gm of pure product, m.p. 180°-182° C.

Workup

  1. customThe product crystallized from solution during the addition
  2. filtrationwas collected by filtration
  3. washwashed with diethyl ether

Sources & evidence

ORD record
ord-bf78132cdaa44872836e427e004f87b4
Source dataset
uspto-grants-1985_02
Patent number
US04497810

Reaction notes

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