Ammonia → HCID 20429203, compound

Participants

Reaction Steps

Analogously to the process described in Example 1 there is obtained from 24.1 g of 2-methylpyridine-6-carboxaldehyde-1-oxide, 40 ml of ethanol, 50.4 ml of ethyl acetoacetate and 20 ml of 25% aqueous ammonia, 2,6-dimethyl-4-(2-methyl-1-oxido-6-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester which, after recrystallisation from ethanol, melts at 224°-225° (with decomposition).

Provenance & Evidence