Ammonia → HCID 20429200, compound

Participants

Reaction Steps

Analogously to the process described in Example 1 there is obtained from 8.4 g of 2-methylpyridine-3-carboxaldehyde-1-oxide, 16.5 ml of ethyl acetoacetate and 6.1 ml of 30% aqueous ammonia in 34 ml of absolute ethanol, 2,6-dimethyl-4-(2-methyl-1-oxido-3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester which, after recrystallisation from 600 ml of acetonitrile, melts at 228°-230°.

Provenance & Evidence