Ammonia → HCID 20429182, compound

Participants

Reaction Steps

Analogously to the process described in Example 1 there is obtained from 8.4 g of 2-chloropyridine-3-carboxaldehyde-1-oxide, 12.75 ml of ethyl acetoacetate and 5 ml of 30% aqueous ammonia in 35 ml of absolute ethanol, 2,6-dimethyl-4-(2-chloro-1-oxido-3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester which, after recrystallisation from 500 ml of isopropanol, melts at 255°-256°.

Provenance & Evidence