Potassium Carbonate → Imiloxan

HRID 615154Notes

Reaction equation

HRID 615154 reaction equation
Cl.[CH2:2]([N:4]1[CH:8]=[CH:7][N:6]=[C:5]1[CH2:9][CH:10]1[O:15][C:14]2[CH:16]=[CH:17][CH:18]=[CH:19][C:13]=2[O:12][CH2:11]1)[CH3:3].C(=O)([O-])[O-].[K+].[K+]>CCOCC>[CH2:2]([N:4]1[CH:8]=[CH:7][N:6]=[C:5]1[CH2:9][CH:10]1[O:15][C:14]2[CH:16]=[CH:17][CH:18]=[CH:19][C:13]=2[O:12][CH2:11]1)[CH3:3]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 172975Imiloxan hydrochloride

Product 1

HCID 133621Imiloxan

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

1-Ethyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole hydrochloride (1.0 g) suspended in 50 ml of ether is stirred with excess dilute aqueous potassium carbonate solution until the salt is completely dissolved. The organic layer is then separated, washed twice with water, dried over magnesium sulfate and evaporated to yield 1-ethyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole, m.p. 77°-78° C.

Workup

  1. dissolutionis completely dissolved
  2. customThe organic layer is then separated
  3. washwashed twice with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

Sources & evidence

ORD record
ord-017b8092784841ff9f77e4fa66544b48
Source dataset
uspto-grants-1985_02
Patent number
US04497818

Reaction notes

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