Isopropyl isocyanate → 1,3,5-Triazino(1,2-a)benzimidazole-10(2H)-carboxamide,3,4-dihydro-2,2,3-trimethyl-N-(1-methylethyl)-4-oxo-

HRID 615287Notes

Reaction equation

[CH3:1][C:2]1([CH3:17])[N:10]([CH3:11])[C:9](=[O:12])[N:8]2[C:4](=[N:5][C:6]3[CH:16]=[CH:15][CH:14]=[CH:13][C:7]=32)[NH:3]1.[CH:18]([N:21]=[C:22]=[O:23])([CH3:20])[CH3:19]>>[CH:18]([NH:21][C:22]([N:5]1[C:6]2[CH:16]=[CH:15][CH:14]=[CH:13][C:7]=2[N:8]2[C:9](=[O:12])[N:10]([CH3:11])[C:2]([CH3:17])([CH3:1])[N:3]=[C:4]12)=[O:23])([CH3:20])[CH3:19]

Participants

Reactant 2

HCID 61277Isopropyl isocyanate

HCID 1591201,2-dihydro-2,2,3-trimethyl-1,3,5-triazino[1,2-a]benzimidazol-4(3H)-one

Product 1

HCID 1591091,3,5-Triazino(1,2-a)benzimidazole-10(2H)-carboxamide,3,4-dihydro-2,2,3-trimethyl-N-(1-methylethyl)-4-oxo-

Procedure

The procedure of Example 10 was used to prepare the title compound from 1,2-dihydro-2,2,3-trimethyl-1,3,5-triazino[1,2-a]benzimidazol-4(3H)-one and isopropyl isocyanate. The product crystallized as a white solid, mp 93°-96° C. The confirmatory elemental analysis is shown in Table III.

Sources & evidence

ORD record: ord-8dde4992074345368041fc241a0de3ed
Source dataset: uspto-grants-1985_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04498920

Reaction notes

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