Methyl iodide → HCID 13387945, compound

Participants

Reaction Steps

A 3.0 g (0.015 mole) amount of 1-[5-methyl-2-(3-pyridinyl)-1H-imidazol-4-yl]ethanone in 300 ml of acetone was treated with 3.0 ml of methyl iodide. The reaction mixture was allowed to stand at room temperature for 24 hours. The precipitate formed was collected by filtration and was washed with 50 ml each of acetone and ether then was dried in vacuo at 60° C. to yield 1.9 g of the desired product as a yellow solid, mp 258°-260° C. (dec.).

Provenance & Evidence