反应详情

温度

-10 °C

A mixture consisting of 7.1 g (0.058 mole) of 3-methyl-4-pyridylmethylamine, 6.25 g (0.051 mole) of 2,3,4-pentanetrione 3-oxime, and 125 ml of acetonitrile was stirred at the reflux temperature for five hours. After cooling at -10° C., a precipitate formed. This was collected, washed with a little cold acetonitrile, and dried. Recrystallization from a mixture of chloroform and hexane gave 4.5 g of the desired product, mp 185°-187° C.

1. customa precipitate formed
2. customThis was collected
3. washwashed with a little cold acetonitrile
4. customdried
5. customRecrystallization
6. additionfrom a mixture of chloroform and hexane