反应详情

Operations are carried out as for Example 7, starting from 2.83 g of 1-(2-chloro phenyl) isoquinoline 3-carboxylic acid, 1.15 g of triethylamine, 1.24 g of ethyl chloroformate and 1.46 g of N-methyl cyclohexylamine in 100 ml of chloroform. 2.45 g of N-cyclohexyl N-methyl 1-(2-chloro phenyl) isoquinoline 3-carboxamide melting at 131° C., are obtained.