反应详情

Operations are carried out as for Example 7, starting from 2.83 g of 1-(2-chloro phenyl) isoquinoline 3-carboxylic acid, 1.17 g of triethylamine, 1.25 g of ethyl chloroformate and 1.31 g of di-isopropylamine in 100 ml of chlorofom. 0.85 g of N,N-di(1-methyl ethyl) 1-(2-chloro phenyl) isoquinoline 3-carboxamide, melting at 161° C., is obtained.