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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 615425Generated: October 31, 2026

Methacryloyl chloride → 12-[(2-Methylacryloyl)amino]dodecanoic acid

https://huagongshe.com/reaction/615425

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethacryloyl chlorideHCID 13528—
Reactant1,4-DioxaneHCID 31275—
Reactant12-Aminododecanoic AcidHCID 69661—
SolventWaterHCID 962—
Product12-[(2-Methylacryloyl)amino]dodecanoic acidHCID 1938658573%

Reaction Steps

0.3 Mole of methacrylic acid chloride and 0.3 mole of 12-aminododecanoic acid were reacted in a mixed solvent of dioxane and water under Schotten Baumann reaction conditions to obtain N-methacryloyl-12-aminododecanoic acid in a yield of 73%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04499251
Source datasetuspto-grants-1985_02
ORD IDord-28794f37e40843cbab20e55e18a8ce7a
Source noteuspto-grants-1985_02