Ethanol → HCID 178472273, compound

HRID 615446Notes

Reaction equation

[F:1][C:2]([F:28])([F:27])[C:3]1[CH:26]=[CH:25][C:6]([O:7][C:8]2[CH:24]=[CH:23][C:11]([O:12][CH:13]([CH3:22])[C:14](=[O:21])[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1.[P:29](Cl)(Cl)(Cl)=[O:30].[CH3:34][OH:35].[CH2:36]([OH:38])[CH3:37]>>[F:1][C:2]([F:27])([F:28])[C:3]1[CH:4]=[CH:5][C:6]([O:7][C:8]2[CH:24]=[CH:23][C:11]([O:12][CH:13]([CH3:22])[C:14]([O:21][PH:29]([O:38][CH2:36][CH2:37][O:35][CH3:34])=[O:30])=[CH:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:10][CH:9]=2)=[CH:25][CH:26]=1

Participants

Reactant 4

HCID 702Ethanol

HCID 887Methanol

HCID 24813Phosphorus oxychloride

HCID 13469151Ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-oxopentanoate

Product 1

HCID 178472273HCID 178472273, compound

Procedure

In the same manner, ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-oxopentanoate is reacted with phosphoryl chloride and then with methanol (1 equiv.) and ethanol (1 equiv.) to give ethyl 4-[4-(4-trifluoromethylphenoxy)phenoxy]-3-methoxyethoxyphosphinyloxy-2-pentenoate (cpd. 7, Table A).

Sources & evidence

ORD record: ord-f3767f89b38c4a93ae73150bd5020b05
Source dataset: uspto-grants-1985_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04499271

Reaction notes

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