HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → Methyl 2-bromo-5-methoxy-4-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-bromo-5-hydroxy-4-methylbenzoate | HCID 20428674 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Methyl 2-bromo-5-methoxy-4-methylbenzoate | HCID 20428669 | — |
Reaction Steps
A mixture of 800 mg of material from step b. 10 ml of dry reagent grade acetone, 456 mg of K2CO3, and excess methyl iodide was stirred a refluxed for 3 days. Ether extraction provided the ester in a form suitable for further transformation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04499299 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-0cae458202b4474b925d7ed95f4d2d05 |
| Source note | uspto-grants-1985_02 |