Ethanol → HCID 178465687, compound

HRID 615652Notes

Reaction equation

HRID 615652 reaction equation
[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:7]([OH:11])=[CH:8][C:9]=1[OH:10])=O.Cl.[OH:13][NH2:14].C([O-])(=O)C.[Na+].C(O)C>O>[CH3:1]/[C:2](/[NH:14][OH:13])=[C:4]1/[CH:5]=[CH:6][C:7]([CH:8]=[C:9]/1[OH:10])=[O:11]

Participants

6

Reactant 4

HCID 702EthanolHCID 69902',4'-DihydroxyacetophenoneHCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium Acetate

Product 1

HCID 178465687HCID 178465687, compoundYield 93.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A mixture of 306 g of 2,4-dihydroxyacetophenone, 164 g of hydroxyamine hydrochloride, 328 g of sodium acetate, 1,000 ml of ethanol and 500 ml of water was refluxed by heating for 4 hours. The reaction solution was poured into 10 l of water to precipitate crystals and these crystals were collected by filtration. 314 g of 2,4-dihydroxyacetophenoneoxime was obtained.

Workup

  1. temperaturewas refluxed
  2. temperatureby heating for 4 hours
  3. customto precipitate crystals
  4. filtrationthese crystals were collected by filtration

Sources & evidence

ORD record
ord-33825d1855174b23b4290e70fd1705e6
Source dataset
uspto-grants-1985_02
Patent number
US04500626

Reaction notes

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