Hydrochloric Acid → HCID 20406529, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (1.0 ml) was added to a stirred suspension of acetaldehyde 4-methyl-2-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)semicarbazone in water (200 ml). The mixture was stirred at room temperature for 3 days, and was filtered. The solid was dried and crystallised from ethyl acetate to give 4-methyl-2-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)semicarbazide (10.0 g) as a white solid, mp 181°-182° C.

Provenance & Evidence