Hydrochloric Acid → HCID 20406529, compound

HRID 615820Notes

Reaction equation

HRID 615820 reaction equation
Cl.[CH3:2][NH:3][C:4](=[O:18])[N:5]([C:9]1[S:10][C:11]([C:14]([F:17])([F:16])[F:15])=[N:12][N:13]=1)[N:6]=CC>O>[CH3:2][NH:3][C:4](=[O:18])[N:5]([C:9]1[S:10][C:11]([C:14]([F:15])([F:16])[F:17])=[N:12][N:13]=1)[NH2:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53677972HCID 53677972, compound

Product 1

HCID 20406529HCID 20406529, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Concentrated hydrochloric acid (1.0 ml) was added to a stirred suspension of acetaldehyde 4-methyl-2-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)semicarbazone in water (200 ml). The mixture was stirred at room temperature for 3 days, and was filtered. The solid was dried and crystallised from ethyl acetate to give 4-methyl-2-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)semicarbazide (10.0 g) as a white solid, mp 181°-182° C.

Workup

  1. filtrationwas filtered
  2. customThe solid was dried
  3. customcrystallised from ethyl acetate

Sources & evidence

ORD record
ord-a46e116cf16c4332b99f5ff40504d8a2
Source dataset
uspto-grants-1985_02
Patent number
US04501605

Reaction notes

Loading…