HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → N-[(3-pyridyl)methyl]-N-(1,1-dimethylethyl)-alpha-(n-butylthio)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | (Butylthio)acetic acid | HCID 88607 | — |
| Reactant | 2-methyl-N-(pyridin-3-ylmethyl)propan-2-amine | HCID 961528 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[(3-pyridyl)methyl]-N-(1,1-dimethylethyl)-alpha-(n-butylthio)acetamide | HCID 13652436 | — |
Reaction Steps
N-[(3-pyridyl)methyl]-N-(1,1-dimethylethyl)-α-(n-butylthio)acetamide was prepared by the method of Example 2 by reacting 8.2 g. of N-[(3-pyridyl)methyl]-(1,1-dimethylethyl)amine with 7.4 g. of α-(n-butylthio)acetic acid and 10.3 g. of N,N'-dicyclohexylcarbodiimide in 150 ml. of dichloromethane. Weight 1.6 g. M.P. 55°-56° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04501746 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-262f376f04704635ae9d1e3c202a97b5 |
| Source note | uspto-grants-1985_02 |