Dicyclohexylcarbodiimide → N-(1-methylhexyl)-N-[(3-pyridyl)methyl]-alpha-(n-butylthio)acetamide

HRID 615876Notes

Reaction equation

HRID 615876 reaction equation
[CH2:1]([S:5][CH2:6][C:7]([OH:9])=O)[CH2:2][CH2:3][CH3:4].C1(N=C=NC2CCCCC2)CCCCC1.[CH3:25][CH:26]([NH:32][CH2:33][C:34]1[CH:35]=[N:36][CH:37]=[CH:38][CH:39]=1)[CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]>ClCCl>[CH3:25][CH:26]([N:32]([CH2:33][C:34]1[CH:35]=[N:36][CH:37]=[CH:38][CH:39]=1)[C:7](=[O:9])[CH2:6][S:5][CH2:1][CH2:2][CH2:3][CH3:4])[CH2:27][CH2:28][CH2:29][CH2:30][CH3:31]

Participants

5

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 88607(Butylthio)acetic acidHCID 147202823-(1-Methylhexylaminomethyl)pyridine

Product 1

HCID 13652437N-(1-methylhexyl)-N-[(3-pyridyl)methyl]-alpha-(n-butylthio)acetamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-(1-methylhexyl)-N-[(3-pyridyl)methyl]-α-(n-butylthio)acetamide was prepared by the method of Example 2 by reacting 3.6 g. of α-(n-butylthio)acetic acid and 5.0 g. of N,N'-dicyclohexylcarbodiimide with 5.0 g. of N-(1-methylhexyl)-[(3-pyridyl)methyl]amine in 200 ml. of dichloromethane. Oil.

Sources & evidence

ORD record
ord-8f1acc1d91fe4a60b4cd80e3e92366a2
Source dataset
uspto-grants-1985_02
Patent number
US04501746

Reaction notes

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