4-Bromobenzoic acid → 4-Bromobenzoyl chloride

HRID 615926Notes

Reaction equation

HRID 615926 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][CH:3]=1.S(Cl)([Cl:13])=O>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:13])=[O:7])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 114644-Bromobenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 685154-Bromobenzoyl chloride

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A solution of 4- bromobenzoic acid (0.113 moles) and thionyl chloride (45 ml) in carbon tetrachloride (100 ml) was heated at reflux for 3.5 hours. Solvent and excess thionyl chloride were removed under reduced pressure and the crude 4-bromobenzoyl chloride was used in subsequent reactions without further purification. ##STR6##

Workup

  1. temperatureat reflux for 3.5 hours
  2. customSolvent and excess thionyl chloride were removed under reduced pressure
  3. customthe crude 4-bromobenzoyl chloride was used in subsequent reactions without further purification

Sources & evidence

ORD record
ord-a18264974c154a02b4c0df0b88307bcb
Source dataset
uspto-grants-1985_02
Patent number
US04501895

Reaction notes

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