Pyridine → HCID 54539334, compound

HRID 615939Notes

Reaction equation

HRID 615939 reaction equation
[CH2:1]1[O:3][CH:2]1[CH2:4][OH:5].N1C=CC=CC=1.[CH3:12][O:13][C:14]([CH2:16][C:17]1[CH:25]=[CH:24][C:20]([C:21](Cl)=[O:22])=[CH:19][CH:18]=1)=[O:15]>CCOCC>[CH3:12][O:13][C:14]([CH2:16][C:17]1[CH:25]=[CH:24][C:20]([C:21]([O:5][CH2:4][CH:2]2[O:3][CH2:1]2)=[O:22])=[CH:19][CH:18]=1)=[O:15]

Participants

5

Reactant 3

HCID 1049PyridineHCID 11164GlycidolHCID 20406944Methyl [4-(chlorocarbonyl)phenyl]acetate

Product 1

HCID 54539334HCID 54539334, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture containing 14.8 g (0.2 mole) of glycidol, 150 ml of anhydrous ether, 16 g (0.4 mole of pyridine and 43 g (0.2 mole) of 4-[(methoxycarbonyl)methyl]benzoyl chloride is stirred at room temperature for two hours. The mixture is filtered and the ether evaporated to leave an oil. This oil is distilled to give a colorless oil.

Workup

  1. filtrationThe mixture is filtered
  2. customthe ether evaporated
  3. customto leave an oil
  4. distillationThis oil is distilled
  5. customto give a colorless oil

Sources & evidence

ORD record
ord-b684324242e74d78bcd633169f3c09aa
Source dataset
uspto-grants-1985_02
Patent number
US04501912

Reaction notes

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