HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178517334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diphenyl Ether | HCID 7583 | — |
| Reactant | 2-Chloro-N-(1H-pyrazol-5-yl)-3-pyridinecarboxamide | HCID 20370814 | — |
| Product | HCID 178517334 | HCID 178517334 | — |
Reaction Steps
103 g. of 2-chloro-N-(1H-pyrazol-5-yl)-3-pyridinecarboxamide are suspended in 600 ml. of diphenyl ether and heated with stirring at 180° until the evolution of HCl gas ceases. After cooling to room temperature, 5-hydroxypyrazolo[1,5-a]pyrido[3,2-e]pyrimidine is filtered off, yield: 75 g. (88%); m.p. ≥ 300° (DMF).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072680 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-6fa4dd07118f4827943d665068b28e59 |
| Source note | uspto-grants-1978_02 |