HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-(1-Ethylpiperidin-3-yl)benzene-1,2-diol--hydrogen bromide (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(3,4-Dimethoxyphenyl)-1-ethylpiperidine | HCID 20370847 | — |
| Product | 4-(1-Ethylpiperidin-3-yl)benzene-1,2-diol--hydrogen bromide (1/1) | HCID 3046374 | — |
Reaction Steps
A mixture of 5.9 g of N-ethyl-3-(3',4'-dimethoxyphenyl)-piperidine and 30 ml of 66% hydrobromic acid was refluxed for an hour and was then evaporated to dryness under reduced pressure. The residue was crystallized from ethanol to obtain 5.9 g of N-ethyl-3-(3',4'-dihydroxyphenyl)-piperidine hydrobromide melting at 207° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072685 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-a8158c60499246db98d207962ae5c7c2 |
| Source note | uspto-grants-1978_02 |