HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-(1-Propylpiperidin-3-yl)benzene-1,2-diol--hydrogen bromide (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Piperidine, 3-(3,4-dimethoxyphenyl)-1-propyl- | HCID 11300035 | — |
| Product | 4-(1-Propylpiperidin-3-yl)benzene-1,2-diol--hydrogen bromide (1/1) | HCID 3046376 | — |
Reaction Steps
A mixture of 4 g of N-propyl-3-(3',4'-dimethoxyphenyl)-piperidine and 40 ml of 66% hydrobromic acid acid was refluxed for an hour and was then evaporated to dryness. The residue was crystallized from isopropanol to obtain 4.4 g of N-propyl-3-(3',4'-dihydroxyphenyl)-piperidine hydrobromide melting at 211° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072685 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-8cd29e1503004a5e9b7e172c91c70ca8 |
| Source note | uspto-grants-1978_02 |