反应详情

A mixture of 4 g of N-propyl-3-(3',4'-dimethoxyphenyl)-piperidine and 40 ml of 66% hydrobromic acid acid was refluxed for an hour and was then evaporated to dryness. The residue was crystallized from isopropanol to obtain 4.4 g of N-propyl-3-(3',4'-dihydroxyphenyl)-piperidine hydrobromide melting at 211° C.

1. temperaturewas refluxed for an hour
2. customwas then evaporated to dryness
3. customThe residue was crystallized from isopropanol