反应详情

A solution of 1.4 g of oxalic acid in 20 ml of isopropanol was added to a solution of 3.5 g of the product of Step A in 20 ml of isopropanol and the mixture was held at 0° C for a few hours and was then vacuum filtered. The crystals were washed with isopropanol and were crystallized from isopropanol to obtain 4.2 g of N-propyl-3-(3',4'-diacetoxyphenyl)-piperidine oxalate melting at 150° C.

1. waitthe mixture was held at 0° C for a few hours
2. filtrationvacuum filtered
3. washThe crystals were washed with isopropanol
4. customwere crystallized from isopropanol