反应详情

A solution of 19.6 g of N-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)formamide in 214 ml of 95% ethanol and 214 ml of 2N hydrochloric acid is heated at reflux for 3 hours and then stirred at room temperature for 2 days. The solution is filtered and the filtrate concentrated in vacuo to afford a dark residue. The residue is dried using ethanol to remove water in vacuo and this procedure affords 20.2 g of the title compound, melting point 200° C to 216° C (dec.).

1. temperatureat reflux for 3 hours
2. filtrationThe solution is filtered
3. concentrationthe filtrate concentrated in vacuo
4. customto afford a dark residue
5. customThe residue is dried
6. customto remove water in vacuo