Ammonia → Mandelamide

HRID 616059Notes

Reaction equation

[C:1]([OH:11])(=O)[CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[OH:3].[NH3:12]>>[C:1]([NH2:12])(=[O:11])[CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[OH:3]

Participants

Reactant 2

HCID 222Ammonia

HCID 1292Mandelic Acid

Product 1

HCID 73558Mandelamide

Procedure

Following Example 10 and replacing the salicylic acid with mandelic acid (1 cmole; 1.521 g) the result is a solution of the corresponding acid chloride which, when treated with ammonia gives mandelamide.

Sources & evidence

ORD record: ord-f0a584ead7794f91af9191181b4c44e8
Source dataset: uspto-grants-1978_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04072710

Reaction notes

Loading…