反应详情

4 G. of 1-amino-2-nitro-4-thiocyanatobenzene is suspended in 12 ml. concentrated hydrochloric acid and cooled to about -40° C. A solution of 24 g. stannous chloride in 12 ml. concentrated hydrochloric acid is added. The mixture is allowed to warm slowly to room temperature and after 20 minutes the product is filtered off and washed with 24 ml. 6N hydrochloric acid. The salt is dissolved in water, treated with potassium bicarbonte, and the mixture extracted with chloroform. Evaporation of the chloroform extracts followed by crystallization of the crude product from benzene yields pure 1,2-diamino-4-thiocyanatobenzene.

1. filtrationis filtered off
2. washwashed with 24 ml
3. dissolutionThe salt is dissolved in water
4. additiontreated with potassium bicarbonte
5. extractionthe mixture extracted with chloroform
6. customEvaporation of the chloroform
7. customextracts followed by crystallization of the crude product from benzene