Sodium Hydroxide → 4-(Butylsulfanyl)-2-nitroaniline

HRID 616089Notes

Reaction equation

HRID 616089 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11][CH2:12][CH2:13][CH2:14][CH3:15])=[CH:7][C:6]=1[N+:16]([O-:18])=[O:17])(=O)C.[OH-].[Na+]>C(O)C>[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([S:11][CH2:12][CH2:13][CH2:14][CH3:15])=[CH:7][C:6]=1[N+:16]([O-:18])=[O:17]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 538046971-Acetamido-4-n-butylthio-2-nitrobenzene

Product 1

HCID 110315614-(Butylsulfanyl)-2-nitroaniline

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3 G. of 1-acetamido-4-n-butylthio-2-nitrobenzene (prepared according to Example I) is hydrolyzed by treatment with 6 ml. 5N NaOH and 6 ml. ethanol on the steam bath for one hour. The mixture is concentrated and extracted with chloroform. Removal of the solvent leaves 1-amino-4-n-butylthio-2-nitrobenzene as a red oil.

Workup

  1. concentrationThe mixture is concentrated
  2. extractionextracted with chloroform
  3. customRemoval of the solvent

Sources & evidence

ORD record
ord-d46ab91787544e69aac2ccfb28b4f5e8
Source dataset
uspto-grants-1978_02
Patent number
US04072696

Reaction notes

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