反应详情

1.5 G. of 1-acetamido-2-nitro-4-methoxymethylthiobenzene, also prepared according to Example VIII, is treated for 4 hours in a refluxing mixture of 160 ml. methanol and 40 ml. water with 4 g. of iron powder (added in two portions) and 1 g. ferrous sulfate. The mixture is filtered, and the filtrate concentrated. The residue is dissolved in chloroform and washed with water, then the solvent evaporated to afford 1-acetamido-2-amino-4-methoxymethylthiobenzene.

1. additionis treated for 4 hours in a refluxing mixture of 160 ml
2. filtrationThe mixture is filtered
3. concentrationthe filtrate concentrated
4. dissolutionThe residue is dissolved in chloroform
5. washwashed with water
6. customthe solvent evaporated