Ethyl bromoacetate → HCID 54118314, compound

HRID 616298Notes

Reaction equation

[CH3:1][O:2][C:3]([CH:5]1[CH:9]([CH2:10][S:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:8][CH2:7][C:6]1=[O:18])=[O:4].Br[CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22].C(=O)([O-])[O-].[K+].[K+]>>[CH3:1][O:2][C:3]([C:5]1([CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH:9]([CH2:10][S:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:8][CH2:7][C:6]1=[O:18])=[O:4]

Participants

Reactant 3

HCID 7748Ethyl bromoacetate

HCID 11430Potassium Carbonate

HCID 54501864HCID 54501864, compound

Product 1

HCID 54118314HCID 54118314, compoundYield 64.2%

Procedure

In accordance with the process of Example 22, 2-oxo-5-phenylthiomethylcyclopentanoic acid methyl ester (792 mg; 3 m mol), ethyl bromoacetate (501 mg; 3 m mol) and potassium carbonate (415 mg; 3 m mol) were used to obtain 674 mg of 1-ethoxycarbonylmethyl-2-oxo-5-phenylthiomethyl-cyclopentanecarboxylic acid methyl ester as a viscous oil.

Sources & evidence

ORD record: ord-b080983054f94b82af6b4b8ca4532ce7
Source dataset: uspto-grants-1978_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04073799

Reaction notes

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